Cargando…

Impact of copy number variant and single nucleotide polymorphism of the programmed death-ligand 1 gene, programmed death-ligand 1 protein expression and therapy regimens on overall survival in a large group of Caucasian patients with non-small cell lung carcinoma

Anti-programmed death-1 or anti-programmed death-ligand 1 (PD-L1) blockade may be ineffective in some patients with non-small cell lung cancer (NSCLC) with high percentage of tumor cells with PD-L1 expression. In addition, immunotherapy may provide great benefits in patients without PD-L1 expression...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grenda, Anna, Krawczyk, Paweł, Kucharczyk, Tomasz, Błach, Justyna, Reszka, Katarzyna, Chmielewska, Izabela, Buczkowski, Jarosław, Kieszko, Robert, Siwiec, Jan, Kubiatowski, Tomasz, Bożyk, Aleksandra, Krukowska, Kinga, Jarosz, Bożena, Paśnik, Iwona, Pankowski, Juliusz, Świniuch, Daria, Stencel, Katarzyna, Gil, Michał, Lew, Kinga, Ramlau, Rodryg, Szczęsna, Aleksandra, Fidler, Sebastian, Sieracki, Andrzej, Każarnowicz, Andrzej, Serwatowski, Piotr, Grodzki, Tomasz, Milanowski, Janusz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045160/ https://www.ncbi.nlm.nih.gov/pubmed/33868487 http://dx.doi.org/10.3892/ol.2021.12710

Ejemplares similares

Tissue MicroRNA Expression as a Predictor of Response to Immunotherapy in NSCLC Patients
por: Grenda, Anna, et al.
Publicado: (2021)

Correlation between KRAS, NRAS and BRAF mutations and tumor localizations in patients with primary and metastatic colorectal cancer
por: Bożyk, Aleksandra, et al.
Publicado: (2021)

An Episode of Pseudothrombocytopenia during Pembrolizumab Therapy in NSCLC Patient
por: Krukowska, Kinga, et al.
Publicado: (2020)

[3-Bromo-2-(3-fluorobenzyloxy)phenyl]boronic acid
por: Kacprzak, Kinga, et al.
Publicado: (2009)

Observational cross-sectional study of 5279 bronchoscopy results for the practical effectiveness of various biopsy techniques in the diagnosis of lung diseases with particular emphasis on lung cancer
por: Błach, Justyna, et al.
Publicado: (2021)

Assessment of EGFR gene mutations in circulating free DNA in monitoring of response to EGFR tyrosine kinase inhibitors in patients with lung adenocarcinoma
por: Nicoś, Marcin, et al.
Publicado: (2019)

Expression of Programmed Death Receptor 1 (PD-1) Gene and Its Ligand (PD-L1) in Patients with Laryngeal Cancer
por: Kowalski, Andrzej, et al.
Publicado: (2021)

A Proliferation-Inducing Ligand and B-Cell Activating Factor Are Upregulated in Patients with Essential Thrombocythemia
por: Bolkun, Lukasz, et al.
Publicado: (2022)

Treatment of Brain Metastases of Non-Small Cell Lung Carcinoma
por: Rybarczyk-Kasiuchnicz, Agnieszka, et al.
Publicado: (2021)

Anti-angiogenic agents in the treatment of non-small cell lung cancer
por: Szyszka-Barth, Katarzyna, et al.
Publicado: (2014)

The assessment of the role of baseline low-dose CT scan in patients at high risk of lung cancer
por: Kołaczyk, Katarzyna, et al.
Publicado: (2014)

Effect of Tryptophan-Derived AhR Ligands, Kynurenine, Kynurenic Acid and FICZ, on Proliferation, Cell Cycle Regulation and Cell Death of Melanoma Cells—In Vitro Studies
por: Walczak, Katarzyna, et al.
Publicado: (2020)

Catalytic residues in hydrolases: analysis of methods designed for ligand-binding site prediction
por: Prymula, Katarzyna, et al.
Publicado: (2010)

Non-Small-Cell Lung Cancer: New Rare Targets—New Targeted Therapies—State of The Art and Future Directions
por: Stencel, Katarzyna, et al.
Publicado: (2021)

Pulmonary Benign Metastasizing Leiomyoma from the Uterine Leiomyoma: A Case Report
por: Kołaczyk, Katarzyna, et al.
Publicado: (2015)

Mediastinal Pancreatic Pseudocysts
por: Dąbkowski, Krzysztof, et al.
Publicado: (2017)

Immunohistochemical assays incorporating SP142 and 22C3 monoclonal antibodies for detection of PD-L1 expression in NSCLC patients with known status of EGFR and ALK genes
por: Krawczyk, Paweł, et al.
Publicado: (2017)

Programmed death ligand-1/programmed death-1 inhibition therapy and programmed death ligand-1 expression in urothelial bladder carcinoma
por: Yu, Wei-Bo, et al.
Publicado: (2019)

Personal fear of death affects the proper process of breaking bad news
por: Ciałkowska-Rysz, Aleksandra, et al.
Publicado: (2013)

Reliability and Repeatability of a Postural Control Test for Preterm Infants
por: Kniaziew-Gomoluch, Katarzyna, et al.
Publicado: (2023)

A New Insight into the Potential Role of Tryptophan-Derived AhR Ligands in Skin Physiological and Pathological Processes
por: Szelest, Monika, et al.
Publicado: (2021)

Neoadjuvant and Adjuvant Immunotherapy in Non-Small Cell Lung Cancer—Clinical Trials Experience
por: Chmielewska, Izabela, et al.
Publicado: (2021)

Gated Resonance Energy Transfer (gRET) Controlled by Programmed Death Protein Ligand 1
por: Grel, Hubert, et al.
Publicado: (2020)

Synthesis, Spectroscopic, Thermal and Catalytic Properties of Four New Metal (II) Complexes with Selected N- and O-Donor Ligands
por: Czylkowska, Agnieszka, et al.
Publicado: (2020)

The efficacy of T790M mutation testing in liquid biopsy—Real clinic data
por: Krawczyk, Paweł, et al.
Publicado: (2022)

Adsorption on Ligand-Tethered Nanoparticles
por: Borówko, Małgorzata, et al.
Publicado: (2021)

Abdominal compartment syndrome – the prevention and treatment of possible lethal complications following hip arthroscopy: a case report
por: Ciemniewska-Gorzela, Kinga, et al.
Publicado: (2014)

UVB Radiation and Selected Tryptophan-Derived AhR Ligands—Potential Biological Interactions in Melanoma Cells
por: Walczak, Katarzyna, et al.
Publicado: (2021)

The Cannabinoid Ligand Arachidonyl-2′-Chloroethylamide (ACEA) Ameliorates Depressive and Overactive Bladder Symptoms in a Corticosterone-Induced Female Wistar Rat Model
por: Zapała, Łukasz, et al.
Publicado: (2023)

Navigating the Shifts: Retrospective Analysis of Alcohol Consumption and its Predictors Across Pre-Pandemic, Lockdown, and Post-Pandemic Eras in Poland
por: Pankowski, Daniel, et al.
Publicado: (2023)

Programmed death‐ligand 1 expression in swine chronic infections and enhancement of interleukin‐2 production via programmed death‐1/programmed death‐ligand 1 blockade
por: Ganbaatar, Otgontuya, et al.
Publicado: (2021)

Imperfect Predictors for Lung Cancer Immunotherapy—A Field for Further Research
por: Wojas-Krawczyk, Kamila, et al.
Publicado: (2020)

Effect of baricitinib in regulating programmed death 1 and ligand programmed cell death ligand 1 through JAK/STAT pathway in psoriasis
por: Deepak, H. B., et al.
Publicado: (2022)

Commercially available SARS-CoV-2 RT-qPCR diagnostic tests need obligatory internal validation
por: Linkowska, Katarzyna, et al.
Publicado: (2023)

Lymph Node Dissection in Upper Tract Urothelial Carcinoma: Current Status and Future Perspectives
por: Dłubak, Andrzej, et al.
Publicado: (2023)

Boussignac CPAP system for brain death confirmation with apneic test in case of acute lung injury/adult respiratory distress syndrome – series of cases
por: Wieczorek, Andrzej, et al.
Publicado: (2015)

Terphenyl-Based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein–Protein Interaction
por: Muszak, Damian, et al.
Publicado: (2021)

Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)
por: Zak, Krzysztof M., et al.
Publicado: (2016)

Inhibition of SREBP1 sensitizes cells to death ligands
por: Eberhard, Yanina, et al.
Publicado: (2011)

Programmed death-ligand 1 expression in rectal cancer
por: Jomrich, G., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_6u7s9qhu2q0c7cr8bk2kcvun73