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Lentivirus-mediated silencing of CNTN1 enhances gefitinib sensitivity by reversing epithelial-mesenchymal transition in lung adenocarcinoma A549 cells
Contactin-1 (CNTN1), a neuronal cell adhesion molecular, functions in nervous system development and has been associated with carcinogenesis and tumor progression. To investigate the role of CNTN1 in gefitinib resistance in lung adenocarcinoma, lentivirus-mediated short hairpin (sh)RNA was used to s...
Autores principales: | Hu, Chun-Sheng, Huang, Jiu-Hong, Yang, Dong-Lin, Xu, Chuan, Xu, Zhi-Gang, Tan, Hong-Bo, Chen, Zhong-Zhu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045161/ https://www.ncbi.nlm.nih.gov/pubmed/33868471 http://dx.doi.org/10.3892/ol.2021.12694 |
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