Gut microbiota accelerates cisplatin-induced acute liver injury associated with robust inflammation and oxidative stress in mice

BACKGROUND: Gut microbiota has been reported to be disrupted by cisplatin, as well as to modulate chemotherapy toxicity. However, the precise role of intestinal microbiota in the pathogenesis of cisplatin hepatotoxicity remains unknown. METHODS: We compared the composition and function of gut microb...

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Detalles Bibliográficos
Autores principales: Gong, Shenhai, Feng, Yinglin, Zeng, Yunong, Zhang, Huanrui, Pan, Meiping, He, Fangjie, Wu, Rong, Chen, Jingrui, Lu, Jiuling, Zhang, Siyou, Yuan, Songhua, Chen, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045234/
https://www.ncbi.nlm.nih.gov/pubmed/33849559
http://dx.doi.org/10.1186/s12967-021-02814-5

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