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The burden attributable to headache disorders in children and adolescents in Lithuania: estimates from a national schools-based study

BACKGROUND: We recently showed headache to be common in children (aged 7–11 years) and adolescents (aged 12–17) in Lithuania. Here we provide evidence from the same study of the headache-attributable burden. METHODS: Following the generic protocol for Lifting The Burden’s global schools-based study,...

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Autores principales: Genc, Diana, Vaičienė-Magistris, Nerija, Zaborskis, Apolinaras, Şaşmaz, Tayyar, Tunç, Aylin Yeniocak, Uluduz, Derya, Wöber, Christian, Wöber-Bingöl, Çiçek, Steiner, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045274/
https://www.ncbi.nlm.nih.gov/pubmed/33849431
http://dx.doi.org/10.1186/s10194-021-01237-3
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author Genc, Diana
Vaičienė-Magistris, Nerija
Zaborskis, Apolinaras
Şaşmaz, Tayyar
Tunç, Aylin Yeniocak
Uluduz, Derya
Wöber, Christian
Wöber-Bingöl, Çiçek
Steiner, Timothy J.
author_facet Genc, Diana
Vaičienė-Magistris, Nerija
Zaborskis, Apolinaras
Şaşmaz, Tayyar
Tunç, Aylin Yeniocak
Uluduz, Derya
Wöber, Christian
Wöber-Bingöl, Çiçek
Steiner, Timothy J.
author_sort Genc, Diana
collection PubMed
description BACKGROUND: We recently showed headache to be common in children (aged 7–11 years) and adolescents (aged 12–17) in Lithuania. Here we provide evidence from the same study of the headache-attributable burden. METHODS: Following the generic protocol for Lifting The Burden’s global schools-based study, this cross-sectional survey administered self-completed structured questionnaires to pupils within classes in 24 nationally representative schools selected from seven regions of the country. Headache diagnostic questions were based on ICHD-3 beta criteria but for the inclusion of undifferentiated headache (UdH; defined as mild headache with usual duration < 1 h). Burden enquiry was conducted in multiple domains. RESULTS: Questionnaires were completed by 2505 pupils (1382 children, 1123 adolescents; participating proportion 67.4%), of whom 1858 reported headache in the preceding year, with mean frequency (±SD) of 3.7 ± 4.5 days/4 weeks and mean duration of 1.6 ± 1.9 h. Mean proportion of time in ictal state, estimated from these, was 0.9% (migraine 1.5%, probable medication-overuse headache [pMOH] 10.9%). Mean intensity on a scale of 1–3 was 1.6 ± 0.6 (mild-to-moderate). Symptomatic medication was consumed on 1.5 ± 2.8 days/4 weeks. Lost school time was 0.5 ± 1.5 days/4 weeks (migraine 0.7 ± 1.5, pMOH 5.0 ± 7.8) based on recall, but about 50% higher for migraine according to actual absences recorded in association with reported headache on the preceding day. More days were reported with limited activity (overall 1.2 ± 2.4, migraine 1.5 ± 2.2, pMOH 8.4 ± 8.5) than lost from school. One in 30 parents (3.3%) missed work at least once in 4 weeks because of their son’s or daughter’s headache. Emotional impact and quality-of-life scores generally reflected other measures of burden, with pMOH causing greatest detriments, followed by migraine and tension-type headache, and UdH least. Burdens were greater in adolescents than children as UdH differentiated into adult headache types. CONCLUSIONS: Headache in children and adolescents in Lithuania is mostly associated with modest symptom burden. However, the consequential burdens, in particular lost school days, are far from negligible for migraine (which is prevalent) and very heavy for pMOH (which, while uncommon in children, becomes four-fold more prevalent in adolescents). These findings are of importance to both health and educational policies in Lithuania.
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spelling pubmed-80452742021-04-14 The burden attributable to headache disorders in children and adolescents in Lithuania: estimates from a national schools-based study Genc, Diana Vaičienė-Magistris, Nerija Zaborskis, Apolinaras Şaşmaz, Tayyar Tunç, Aylin Yeniocak Uluduz, Derya Wöber, Christian Wöber-Bingöl, Çiçek Steiner, Timothy J. J Headache Pain Research Article BACKGROUND: We recently showed headache to be common in children (aged 7–11 years) and adolescents (aged 12–17) in Lithuania. Here we provide evidence from the same study of the headache-attributable burden. METHODS: Following the generic protocol for Lifting The Burden’s global schools-based study, this cross-sectional survey administered self-completed structured questionnaires to pupils within classes in 24 nationally representative schools selected from seven regions of the country. Headache diagnostic questions were based on ICHD-3 beta criteria but for the inclusion of undifferentiated headache (UdH; defined as mild headache with usual duration < 1 h). Burden enquiry was conducted in multiple domains. RESULTS: Questionnaires were completed by 2505 pupils (1382 children, 1123 adolescents; participating proportion 67.4%), of whom 1858 reported headache in the preceding year, with mean frequency (±SD) of 3.7 ± 4.5 days/4 weeks and mean duration of 1.6 ± 1.9 h. Mean proportion of time in ictal state, estimated from these, was 0.9% (migraine 1.5%, probable medication-overuse headache [pMOH] 10.9%). Mean intensity on a scale of 1–3 was 1.6 ± 0.6 (mild-to-moderate). Symptomatic medication was consumed on 1.5 ± 2.8 days/4 weeks. Lost school time was 0.5 ± 1.5 days/4 weeks (migraine 0.7 ± 1.5, pMOH 5.0 ± 7.8) based on recall, but about 50% higher for migraine according to actual absences recorded in association with reported headache on the preceding day. More days were reported with limited activity (overall 1.2 ± 2.4, migraine 1.5 ± 2.2, pMOH 8.4 ± 8.5) than lost from school. One in 30 parents (3.3%) missed work at least once in 4 weeks because of their son’s or daughter’s headache. Emotional impact and quality-of-life scores generally reflected other measures of burden, with pMOH causing greatest detriments, followed by migraine and tension-type headache, and UdH least. Burdens were greater in adolescents than children as UdH differentiated into adult headache types. CONCLUSIONS: Headache in children and adolescents in Lithuania is mostly associated with modest symptom burden. However, the consequential burdens, in particular lost school days, are far from negligible for migraine (which is prevalent) and very heavy for pMOH (which, while uncommon in children, becomes four-fold more prevalent in adolescents). These findings are of importance to both health and educational policies in Lithuania. Springer Milan 2021-04-13 /pmc/articles/PMC8045274/ /pubmed/33849431 http://dx.doi.org/10.1186/s10194-021-01237-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Genc, Diana
Vaičienė-Magistris, Nerija
Zaborskis, Apolinaras
Şaşmaz, Tayyar
Tunç, Aylin Yeniocak
Uluduz, Derya
Wöber, Christian
Wöber-Bingöl, Çiçek
Steiner, Timothy J.
The burden attributable to headache disorders in children and adolescents in Lithuania: estimates from a national schools-based study
title The burden attributable to headache disorders in children and adolescents in Lithuania: estimates from a national schools-based study
title_full The burden attributable to headache disorders in children and adolescents in Lithuania: estimates from a national schools-based study
title_fullStr The burden attributable to headache disorders in children and adolescents in Lithuania: estimates from a national schools-based study
title_full_unstemmed The burden attributable to headache disorders in children and adolescents in Lithuania: estimates from a national schools-based study
title_short The burden attributable to headache disorders in children and adolescents in Lithuania: estimates from a national schools-based study
title_sort burden attributable to headache disorders in children and adolescents in lithuania: estimates from a national schools-based study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045274/
https://www.ncbi.nlm.nih.gov/pubmed/33849431
http://dx.doi.org/10.1186/s10194-021-01237-3
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