ROSE in Rosai–Dorfman–Destombes (RDD) disease: a cytological diagnosis

BACKGROUND: Rosai–Dorfman–Destombes (RDD) is also known as sinus histiocytosis with massive lymphadenopathy (SHML). It is a benign proliferative disorder of histiocytes, affecting lymph nodes, rarely with extra-nodal involvement. Rapid on-site evaluation (ROSE) with fine-needle aspiration cytology (...

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Detalles Bibliográficos
Autores principales: Tummidi, Santosh, Singh, Hemant Kumar, Reddy, Prudhvinath A, Sindhura, Manda, Kosaraju, Navya, Shankaralingappa, Arundhathi, Kumar, Naresh P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045294/
https://www.ncbi.nlm.nih.gov/pubmed/33849657
http://dx.doi.org/10.1186/s40001-021-00505-x
Descripción
Sumario:BACKGROUND: Rosai–Dorfman–Destombes (RDD) is also known as sinus histiocytosis with massive lymphadenopathy (SHML). It is a benign proliferative disorder of histiocytes, affecting lymph nodes, rarely with extra-nodal involvement. Rapid on-site evaluation (ROSE) with fine-needle aspiration cytology (FNAC) can be utilized as a minimally invasive investigation to avoid unnecessary surgery of this self-limiting disease. CASE PRESENTATION: A 65-year-old female presented with complaints of bilateral cervical lymphadenopathy since 1 year. Rapid on-site stain with FNAC from bilateral cervical lymph nodes revealed features of Rosai–Dorfman–Destombes (RDD) disease. CONCLUSION: FNAC with rapid on-site evaluation can provide a simple and cost-effective method for looking at the unique cytological features of the disease and act as a first-line investigation.

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