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Phase I dose-escalation oncology trials with sequential multiple schedules
BACKGROUND: Conventional methods for phase I dose-escalation trials in oncology are based on a single treatment schedule only. More recently, however, multiple schedules are more frequently investigated in the same trial. METHODS: Here, we consider sequential phase I trials, where the trial proceeds...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045405/ https://www.ncbi.nlm.nih.gov/pubmed/33853539 http://dx.doi.org/10.1186/s12874-021-01218-9 |