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A Bayesian Mixture Model for Predicting the COVID-19 Related Mortality in the United States

An outbreak of SARS-CoV-2 has led to a global pandemic affecting virtually every country. As of August 31, 2020, globally, there have been approximately 25,500,000 confirmed cases and 850,000 deaths; in the United States (50 states plus District of Columbia), there have been more than 6,000,000 conf...

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Autores principales: Kaciroti, Niko A., Lumeng, Carey, Parekh, Vikas, Boulton, Matthew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045639/
https://www.ncbi.nlm.nih.gov/pubmed/33606666
http://dx.doi.org/10.4269/ajtmh.20-1147
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author Kaciroti, Niko A.
Lumeng, Carey
Parekh, Vikas
Boulton, Matthew L.
author_facet Kaciroti, Niko A.
Lumeng, Carey
Parekh, Vikas
Boulton, Matthew L.
author_sort Kaciroti, Niko A.
collection PubMed
description An outbreak of SARS-CoV-2 has led to a global pandemic affecting virtually every country. As of August 31, 2020, globally, there have been approximately 25,500,000 confirmed cases and 850,000 deaths; in the United States (50 states plus District of Columbia), there have been more than 6,000,000 confirmed cases and 183,000 deaths. We propose a Bayesian mixture model to predict and monitor COVID-19 mortality across the United States. The model captures skewed unimodal (prolonged recovery) or multimodal (multiple surges) curves. The results show that across all states, the first peak dates of mortality varied between April 4, 2020 for Alaska and June 18, 2020 for Arkansas. As of August 31, 2020, 31 states had a clear bimodal curve showing a strong second surge. The peak date for a second surge ranged from July 1, 2020 for Virginia to September 12, 2020 for Hawaii. The first peak for the United States occurred about April 16, 2020—dominated by New York and New Jersey—and a second peak on August 6, 2020—dominated by California, Texas, and Florida. Reliable models for predicting the COVID-19 pandemic are essential to informing resource allocation and intervention strategies. A Bayesian mixture model was able to more accurately predict the shape of the mortality curves across the United States than other models, including the timing of multiple peaks. However, given the dynamic nature of the pandemic, it is important that the results be updated regularly to identify and better monitor future waves, and characterize the epidemiology of the pandemic.
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spelling pubmed-80456392021-04-19 A Bayesian Mixture Model for Predicting the COVID-19 Related Mortality in the United States Kaciroti, Niko A. Lumeng, Carey Parekh, Vikas Boulton, Matthew L. Am J Trop Med Hyg Articles An outbreak of SARS-CoV-2 has led to a global pandemic affecting virtually every country. As of August 31, 2020, globally, there have been approximately 25,500,000 confirmed cases and 850,000 deaths; in the United States (50 states plus District of Columbia), there have been more than 6,000,000 confirmed cases and 183,000 deaths. We propose a Bayesian mixture model to predict and monitor COVID-19 mortality across the United States. The model captures skewed unimodal (prolonged recovery) or multimodal (multiple surges) curves. The results show that across all states, the first peak dates of mortality varied between April 4, 2020 for Alaska and June 18, 2020 for Arkansas. As of August 31, 2020, 31 states had a clear bimodal curve showing a strong second surge. The peak date for a second surge ranged from July 1, 2020 for Virginia to September 12, 2020 for Hawaii. The first peak for the United States occurred about April 16, 2020—dominated by New York and New Jersey—and a second peak on August 6, 2020—dominated by California, Texas, and Florida. Reliable models for predicting the COVID-19 pandemic are essential to informing resource allocation and intervention strategies. A Bayesian mixture model was able to more accurately predict the shape of the mortality curves across the United States than other models, including the timing of multiple peaks. However, given the dynamic nature of the pandemic, it is important that the results be updated regularly to identify and better monitor future waves, and characterize the epidemiology of the pandemic. The American Society of Tropical Medicine and Hygiene 2021-04 2021-02-19 /pmc/articles/PMC8045639/ /pubmed/33606666 http://dx.doi.org/10.4269/ajtmh.20-1147 Text en © The American Society of Tropical Medicine and Hygiene https://creativecommons.org/licenses/by-nc/4.0/Open Access statement. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and reproduction in any medium for non-commercial purposes, provided the original author and source are credited, a link to the CC License is provided, and changes – if any – are indicated.
spellingShingle Articles
Kaciroti, Niko A.
Lumeng, Carey
Parekh, Vikas
Boulton, Matthew L.
A Bayesian Mixture Model for Predicting the COVID-19 Related Mortality in the United States
title A Bayesian Mixture Model for Predicting the COVID-19 Related Mortality in the United States
title_full A Bayesian Mixture Model for Predicting the COVID-19 Related Mortality in the United States
title_fullStr A Bayesian Mixture Model for Predicting the COVID-19 Related Mortality in the United States
title_full_unstemmed A Bayesian Mixture Model for Predicting the COVID-19 Related Mortality in the United States
title_short A Bayesian Mixture Model for Predicting the COVID-19 Related Mortality in the United States
title_sort bayesian mixture model for predicting the covid-19 related mortality in the united states
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045639/
https://www.ncbi.nlm.nih.gov/pubmed/33606666
http://dx.doi.org/10.4269/ajtmh.20-1147
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