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The Metabolic Landscape of RAS-Driven Cancers from biology to therapy

Our understanding of how the RAS protein family, and in particular mutant KRAS promote metabolic dysregulation in cancer cells has advanced significantly over the last decade. In this Review, we discuss the metabolic reprogramming mediated by oncogenic RAS in cancer, and elucidating the underlying m...

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Detalles Bibliográficos
Autores principales: Mukhopadhyay, Suman, Vander Heiden, Matthew G., McCormick, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045781/
https://www.ncbi.nlm.nih.gov/pubmed/33870211
http://dx.doi.org/10.1038/s43018-021-00184-x