NAD(+) supplementation prevents STING‐induced senescence in ataxia telangiectasia by improving mitophagy

Senescence phenotypes and mitochondrial dysfunction are implicated in aging and in premature aging diseases, including ataxia telangiectasia (A‐T). Loss of mitochondrial function can drive age‐related decline in the brain, but little is known about whether improving mitochondrial homeostasis allevia...

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Detalles Bibliográficos
Autores principales: Yang, Beimeng, Dan, Xiuli, Hou, Yujun, Lee, Jong‐Hyuk, Wechter, Noah, Krishnamurthy, Sudarshan, Kimura, Risako, Babbar, Mansi, Demarest, Tyler, McDevitt, Ross, Zhang, Shiliang, Zhang, Yongqing, Mattson, Mark P., Croteau, Deborah L., Bohr, Vilhelm A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045911/
https://www.ncbi.nlm.nih.gov/pubmed/33734555
http://dx.doi.org/10.1111/acel.13329

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