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QSM is an imaging biomarker for chronic glial activation in multiple sclerosis lesions

BACKGROUND: Inflammation in chronic active lesions occurs behind a closed blood–brain barrier and cannot be detected with MRI. Activated microglia are highly enriched for iron and can be visualized with quantitative susceptibility mapping (QSM), an MRI technique used to delineate iron. OBJECTIVE: To...

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Detalles Bibliográficos
Autores principales:	Gillen, Kelly M., Mubarak, Mayyan, Park, Calvin, Ponath, Gerald, Zhang, Shun, Dimov, Alexey, Levine‐Ritterman, Maya, Toro, Steven, Huang, Weiyuan, Amici, Stephanie, Kaunzner, Ulrike W., Gauthier, Susan A., Guerau‐de‐Arellano, Mireia, Wang, Yi, Nguyen, Thanh D., Pitt, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045922/ https://www.ncbi.nlm.nih.gov/pubmed/33704933 http://dx.doi.org/10.1002/acn3.51338

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