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Physiological and metabolic characteristics of novel double‐mutant female mice with targeted disruption of both growth hormone‐releasing hormone and growth hormone receptor

Mice with disruptions of growth hormone‐releasing hormone (GHRH) or growth hormone receptor (GHR) exhibit similar phenotypes of prolonged lifespan and delayed age‐related diseases. However, these two models respond differently to calorie restriction indicating that they might carry different and/or...

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Detalles Bibliográficos
Autores principales: Icyuz, Mert, Zhang, Fang, Fitch, Michael P., Joyner, Matthew R., Challa, Anil K., Sun, Liou Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045953/
https://www.ncbi.nlm.nih.gov/pubmed/33755309
http://dx.doi.org/10.1111/acel.13339