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CaMKII holoenzyme mechanisms that govern the LTP versus LTD decision

Higher brain functions are thought to require synaptic frequency decoding that can lead to long-term potentiation (LTP) or depression (LTD). We show that the LTP versus LTD decision is determined by complex cross-regulation of T286 and T305/306 autophosphorylation within the 12meric CaMKII holoenzym...

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Detalles Bibliográficos
Autores principales:	Cook, Sarah G., Buonarati, Olivia R., Coultrap, Steven J., Bayer, K. Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046365/ https://www.ncbi.nlm.nih.gov/pubmed/33853773 http://dx.doi.org/10.1126/sciadv.abe2300

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