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Mouse aging cell atlas analysis reveals global and cell type-specific aging signatures

Aging is associated with complex molecular and cellular processes that are poorly understood. Here we leveraged the Tabula Muris Senis single-cell RNA-seq data set to systematically characterize gene expression changes during aging across diverse cell types in the mouse. We identified aging-dependen...

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Detalles Bibliográficos
Autores principales:	Zhang, Martin Jinye, Pisco, Angela Oliveira, Darmanis, Spyros, Zou, James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046488/ https://www.ncbi.nlm.nih.gov/pubmed/33847263 http://dx.doi.org/10.7554/eLife.62293

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