Antiviral strategies should focus on stimulating the biosynthesis of heparan sulfates, not their inhibition

Antiviral strategies for viruses that utilize proteoglycan core proteins (syndecans and glypicans) as receptors should focus on heparan sulfate (HS) biosynthesis rather than on inhibition of these sugar chains. Here, we show that heparin and certain xylosides, which exhibit in vitro viral entry inhi...

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Detalles Bibliográficos
Autor principal: Cheudjeu, Antony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046744/
https://www.ncbi.nlm.nih.gov/pubmed/33865880
http://dx.doi.org/10.1016/j.lfs.2021.119508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046744/
https://www.ncbi.nlm.nih.gov/pubmed/33865880
http://dx.doi.org/10.1016/j.lfs.2021.119508

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