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Antiviral strategies should focus on stimulating the biosynthesis of heparan sulfates, not their inhibition
Antiviral strategies for viruses that utilize proteoglycan core proteins (syndecans and glypicans) as receptors should focus on heparan sulfate (HS) biosynthesis rather than on inhibition of these sugar chains. Here, we show that heparin and certain xylosides, which exhibit in vitro viral entry inhi...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Inc.
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046744/ https://www.ncbi.nlm.nih.gov/pubmed/33865880 http://dx.doi.org/10.1016/j.lfs.2021.119508 |