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TIM-3 drives temporal differences in restimulation-induced cell death sensitivity in effector CD8(+) T cells in conjunction with CEACAM1
Immune homeostasis depends upon effective clearance of pathogens while simultaneously preventing autoimmunity and immunopathology in the host. Restimulation-induced cell death (RICD) is one such mechanism where by activated T cells receive subsequent antigenic stimulation, reach a critical signal th...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046753/ https://www.ncbi.nlm.nih.gov/pubmed/33854046 http://dx.doi.org/10.1038/s41419-021-03689-6 |