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TIM-3 drives temporal differences in restimulation-induced cell death sensitivity in effector CD8(+) T cells in conjunction with CEACAM1

Immune homeostasis depends upon effective clearance of pathogens while simultaneously preventing autoimmunity and immunopathology in the host. Restimulation-induced cell death (RICD) is one such mechanism where by activated T cells receive subsequent antigenic stimulation, reach a critical signal th...

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Detalles Bibliográficos
Autores principales: Lake, Camille M., Voss, Kelsey, Bauman, Bradly M., Pohida, Katherine, Jiang, Timothy, Dveksler, Gabriela, Snow, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046753/
https://www.ncbi.nlm.nih.gov/pubmed/33854046
http://dx.doi.org/10.1038/s41419-021-03689-6

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