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Optimisation of a PC12 cell-based in vitro stroke model for screening neuroprotective agents
Stroke causes death and disability globally but no neuroprotectant is approved for post-stroke neuronal injury. Neuroprotective compounds can be identified using oxygen glucose deprivation (OGD) of neuronal cells as an in vitro stroke model. Nerve growth factor (NGF)-differentiated PC12 pheochromocy...
Autores principales: | Chua, PinFen, Lim, William K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046774/ https://www.ncbi.nlm.nih.gov/pubmed/33854099 http://dx.doi.org/10.1038/s41598-021-87431-4 |
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