Accelerated phase Ia/b evaluation of the malaria vaccine candidate PfAMA1 DiCo demonstrates broadening of humoral immune responses

Plasmodium falciparum apical membrane antigen 1 (PfAMA1) is a candidate malaria vaccine antigen expressed on merozoites and sporozoites. PfAMA1’s polymorphic nature impacts vaccine-induced protection. To address polymorphism, three Diversity Covering (DiCo) protein sequences were designed and tested...

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Detalles Bibliográficos
Autores principales: Remarque, Edmond J., Faber, Bart W., Rodriguez Garcia, Roberto, Oostermeijer, Herman, Sirima, Sodiomon B., Nebie Ouedraogo, Issa, Kara, Leila, Launay, Odile, Houard, Sophie, Leroy, Odile, Kocken, Clemens H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046791/
https://www.ncbi.nlm.nih.gov/pubmed/33854065
http://dx.doi.org/10.1038/s41541-021-00319-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046791/
https://www.ncbi.nlm.nih.gov/pubmed/33854065
http://dx.doi.org/10.1038/s41541-021-00319-2

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