TIM4 expression by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses

Acquisition of cell-associated tumor antigens by type 1 dendritic cells (cDC1) is essential to induce and sustain tumor specific CD8(+) T cells via cross-presentation. Here we show that capture and engulfment of cell associated antigens by tissue resident lung cDC1 is inhibited during progression of...

Descripción completa

Detalles Bibliográficos
Autores principales: Caronni, Nicoletta, Piperno, Giulia Maria, Simoncello, Francesca, Romano, Oriana, Vodret, Simone, Yanagihashi, Yuichi, Dress, Regine, Dutertre, Charles-Antoine, Bugatti, Mattia, Bourdeley, Pierre, Del Prete, Annalisa, Schioppa, Tiziana, Mazza, Emilia Maria Cristina, Collavin, Licio, Zacchigna, Serena, Ostuni, Renato, Guermonprez, Pierre, Vermi, William, Ginhoux, Florent, Bicciato, Silvio, Nagata, Shigekatzu, Benvenuti, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046802/
https://www.ncbi.nlm.nih.gov/pubmed/33854047
http://dx.doi.org/10.1038/s41467-021-22535-z

Ejemplares similares

Ejemplares similares