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Western Diet Induces Impairment of Liver-Brain Axis Accelerating Neuroinflammation and Amyloid Pathology in Alzheimer's Disease

Alzheimer's disease (AD) is an aging-dependent, irreversible neurodegenerative disorder and the most common cause of dementia. The prevailing AD hypothesis points to the central role of altered cleavage of amyloid precursor protein (APP) and formation of toxic amyloid-β (Aβ) deposits in the bra...

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Detalles Bibliográficos
Autores principales: Wiȩckowska-Gacek, Angelika, Mietelska-Porowska, Anna, Chutorański, Dominik, Wydrych, Małgorzata, Długosz, Jan, Wojda, Urszula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046915/
https://www.ncbi.nlm.nih.gov/pubmed/33867971
http://dx.doi.org/10.3389/fnagi.2021.654509