Cargando…
Directly targeting c-Myc contributes to the anti-multiple myeloma effect of anlotinib
Despite the significant advances in the treatment of multiple myeloma (MM), this disease is still considered incurable because of relapse and chemotherapy resistance, underscoring the need to seek novel therapies with different mechanisms. Anlotinib, a novel multi-targeted tyrosine kinase inhibitor...
Autores principales: | Cao, Yang, Shan, Huizhuang, Liu, Meng, Liu, Jia, Zhang, Zilu, Xu, Xiaoguang, Liu, Yue, Xu, Hanzhang, Lei, Hu, Yu, Miao, Zhang, Xingming, Liu, Wanting, Bu, Zhilei, Fang, Zhixiao, Ji, Yanjie, Yan, Hua, Gu, Weiying, Wu, Yingli |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046985/ https://www.ncbi.nlm.nih.gov/pubmed/33854043 http://dx.doi.org/10.1038/s41419-021-03685-w |
Ejemplares similares
-
IKZF1 selectively enhances homologous recombination repair by interacting with CtIP and USP7 in multiple myeloma
por: Liu, Meng, et al.
Publicado: (2022) -
YL064 activates proteasomal-dependent degradation of c-Myc and synergistically enhances the anti-tumor activity of ABT-199 in diffuse large B cell lymphoma
por: Shan, Huizhuang, et al.
Publicado: (2020) -
Novel myeloma patient-derived xenograft models unveil the potency of anlotinib to overcome bortezomib resistance
por: Yue, Yanhua, et al.
Publicado: (2022) -
JaponiconeA induces apoptosis of bortezomib-sensitive and -resistant myeloma cells in vitro and in vivo by targeting IKKβ
por: Zhang, Zilu, et al.
Publicado: (2022) -
Hypoxia-induced long non-coding RNA DARS-AS1 regulates RBM39 stability to promote myeloma malignancy
por: Tong, Jia, et al.
Publicado: (2020)