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VectorMOD: Method for Bottom-Up Proteomic Characterization of rAAV Capsid Post-Translational Modifications and Vector Impurities

Progress in recombinant AAV gene therapy product and process development has advanced our understanding of the basic biology of this critical delivery vector. The discovery of rAAV capsid post-translational modifications (PTMs) has spurred interest in the field for detailed rAAV-specific methods for...

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Detalles Bibliográficos
Autores principales:	Rumachik, Neil G., Malaker, Stacy A., Paulk, Nicole K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047074/ https://www.ncbi.nlm.nih.gov/pubmed/33868302 http://dx.doi.org/10.3389/fimmu.2021.657795

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