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CRISPR/Cas9-Mediated α-ENaC Knockout in a Murine Pancreatic β-Cell Line

Many ion channels participate in controlling insulin synthesis and secretion of pancreatic β-cells. Epithelial sodium channel (ENaC) expressed in human pancreatic tissue, but the biological role of ENaC in pancreatic β-cells is still unclear. Here, we applied the CRISPR/Cas9 gene editing technique t...

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Detalles Bibliográficos
Autores principales:	Zhang, Xue, Zhao, Lihua, Jin, Runbing, Li, Min, Li, Mei-Shuang, Li, Rongfeng, Liang, Xiubin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047203/ https://www.ncbi.nlm.nih.gov/pubmed/33868391 http://dx.doi.org/10.3389/fgene.2021.664799

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