Inhibiting miR-22 Alleviates Cardiac Dysfunction by Regulating Sirt1 in Septic Cardiomyopathy

High morbidity and mortality are the most typical characteristics of septic cardiomyopathy. We aimed to reveal the role of miR-22 in septic cardiomyopathy and to explore the underlying mechanisms. miR-22 cardiac-specific knockout (miR-22(cKO)) mice and miR-22 cardiac-specific transgenic (miR-22(cOE)...

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Detalles Bibliográficos
Autores principales: Wang, Runze, Xu, Yuerong, Zhang, Wei, Fang, Yexian, Yang, Tiqun, Zeng, Di, Wei, Ting, Liu, Jing, Zhou, Haijia, Li, Yan, Huang, Zhan-peng, Zhang, Mingming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047209/
https://www.ncbi.nlm.nih.gov/pubmed/33869205
http://dx.doi.org/10.3389/fcell.2021.650666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047209/
https://www.ncbi.nlm.nih.gov/pubmed/33869205
http://dx.doi.org/10.3389/fcell.2021.650666

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