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Inhibiting miR-22 Alleviates Cardiac Dysfunction by Regulating Sirt1 in Septic Cardiomyopathy

High morbidity and mortality are the most typical characteristics of septic cardiomyopathy. We aimed to reveal the role of miR-22 in septic cardiomyopathy and to explore the underlying mechanisms. miR-22 cardiac-specific knockout (miR-22(cKO)) mice and miR-22 cardiac-specific transgenic (miR-22(cOE)...

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Detalles Bibliográficos
Autores principales:	Wang, Runze, Xu, Yuerong, Zhang, Wei, Fang, Yexian, Yang, Tiqun, Zeng, Di, Wei, Ting, Liu, Jing, Zhou, Haijia, Li, Yan, Huang, Zhan-peng, Zhang, Mingming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047209/ https://www.ncbi.nlm.nih.gov/pubmed/33869205 http://dx.doi.org/10.3389/fcell.2021.650666

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