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Using Domain Based Latent Personal Analysis of B Cell Clone Diversity Patterns to Identify Novel Relationships Between the B Cell Clone Populations in Different Tissues

The B cell population is highly diverse and very skewed. It is divided into clones (B cells with a common mother cell). It is thought that each clone represents an initial B cell receptor specificity. A few clones are very abundant, comprised of hundreds or thousands of B cells while the majority ha...

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Detalles Bibliográficos
Autores principales: Alon, Uri, Mokryn, Osnat, Hershberg, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047331/
https://www.ncbi.nlm.nih.gov/pubmed/33868278
http://dx.doi.org/10.3389/fimmu.2021.642673