Impaired diffusing capacity for carbon monoxide is common in critically ill Covid-19 patients at four months post-discharge

There is limited knowledge about the long-term effects on pulmonary function of COVID-19 in patients that required intensive care treatment. Spirometry and diffusing capacity for carbon monoxide (DLCO) were measured in 60 subjects at 3-6 months post discharge. Impaired lung function was found in 52%...

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Detalles Bibliográficos
Autores principales: E, Ekbom, R, Frithiof, Öi, Emilsson, IM, Larson, M, Lipcsey, S, Rubertsson, E, Wallin, C, Janson, M, Hultström, A, Malinovschi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047337/
https://www.ncbi.nlm.nih.gov/pubmed/33901787
http://dx.doi.org/10.1016/j.rmed.2021.106394
Descripción
Sumario:There is limited knowledge about the long-term effects on pulmonary function of COVID-19 in patients that required intensive care treatment. Spirometry and diffusing capacity for carbon monoxide (DLCO) were measured in 60 subjects at 3-6 months post discharge. Impaired lung function was found in 52% of the subjects, with reduced DLCO as the main finding. The risk increased with age above 60 years, need for mechanical ventilation and longer ICU stay as well as lower levels of C-reactive protein at admission. This suggests the need of follow-up with pulmonary function testing in intensive-care treated patients.

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