Impaired diffusing capacity for carbon monoxide is common in critically ill Covid-19 patients at four months post-discharge

There is limited knowledge about the long-term effects on pulmonary function of COVID-19 in patients that required intensive care treatment. Spirometry and diffusing capacity for carbon monoxide (DLCO) were measured in 60 subjects at 3-6 months post discharge. Impaired lung function was found in 52%...

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Autores principales: E, Ekbom, R, Frithiof, Öi, Emilsson, IM, Larson, M, Lipcsey, S, Rubertsson, E, Wallin, C, Janson, M, Hultström, A, Malinovschi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047337/
https://www.ncbi.nlm.nih.gov/pubmed/33901787
http://dx.doi.org/10.1016/j.rmed.2021.106394
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author E, Ekbom
R, Frithiof
Öi, Emilsson
IM, Larson
M, Lipcsey
S, Rubertsson
E, Wallin
C, Janson
M, Hultström
A, Malinovschi
author_facet E, Ekbom
R, Frithiof
Öi, Emilsson
IM, Larson
M, Lipcsey
S, Rubertsson
E, Wallin
C, Janson
M, Hultström
A, Malinovschi
author_sort E, Ekbom
collection PubMed
description There is limited knowledge about the long-term effects on pulmonary function of COVID-19 in patients that required intensive care treatment. Spirometry and diffusing capacity for carbon monoxide (DLCO) were measured in 60 subjects at 3-6 months post discharge. Impaired lung function was found in 52% of the subjects, with reduced DLCO as the main finding. The risk increased with age above 60 years, need for mechanical ventilation and longer ICU stay as well as lower levels of C-reactive protein at admission. This suggests the need of follow-up with pulmonary function testing in intensive-care treated patients.
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spelling pubmed-80473372021-04-15 Impaired diffusing capacity for carbon monoxide is common in critically ill Covid-19 patients at four months post-discharge E, Ekbom R, Frithiof Öi, Emilsson IM, Larson M, Lipcsey S, Rubertsson E, Wallin C, Janson M, Hultström A, Malinovschi Respir Med Short Communication There is limited knowledge about the long-term effects on pulmonary function of COVID-19 in patients that required intensive care treatment. Spirometry and diffusing capacity for carbon monoxide (DLCO) were measured in 60 subjects at 3-6 months post discharge. Impaired lung function was found in 52% of the subjects, with reduced DLCO as the main finding. The risk increased with age above 60 years, need for mechanical ventilation and longer ICU stay as well as lower levels of C-reactive protein at admission. This suggests the need of follow-up with pulmonary function testing in intensive-care treated patients. The Authors. Published by Elsevier Ltd. 2021-06 2021-04-15 /pmc/articles/PMC8047337/ /pubmed/33901787 http://dx.doi.org/10.1016/j.rmed.2021.106394 Text en © 2021 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Communication
E, Ekbom
R, Frithiof
Öi, Emilsson
IM, Larson
M, Lipcsey
S, Rubertsson
E, Wallin
C, Janson
M, Hultström
A, Malinovschi
Impaired diffusing capacity for carbon monoxide is common in critically ill Covid-19 patients at four months post-discharge
title Impaired diffusing capacity for carbon monoxide is common in critically ill Covid-19 patients at four months post-discharge
title_full Impaired diffusing capacity for carbon monoxide is common in critically ill Covid-19 patients at four months post-discharge
title_fullStr Impaired diffusing capacity for carbon monoxide is common in critically ill Covid-19 patients at four months post-discharge
title_full_unstemmed Impaired diffusing capacity for carbon monoxide is common in critically ill Covid-19 patients at four months post-discharge
title_short Impaired diffusing capacity for carbon monoxide is common in critically ill Covid-19 patients at four months post-discharge
title_sort impaired diffusing capacity for carbon monoxide is common in critically ill covid-19 patients at four months post-discharge
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047337/
https://www.ncbi.nlm.nih.gov/pubmed/33901787
http://dx.doi.org/10.1016/j.rmed.2021.106394
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