Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency

In the mammalian embryo, epiblast cells must exit the naïve state and acquire formative pluripotency. This cell state transition is recapitulated by mouse embryonic stem cells (ESCs), which undergo pluripotency progression in defined conditions in vitro. However, our understanding of the molecular c...

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Detalles Bibliográficos
Autores principales: Lackner, Andreas, Sehlke, Robert, Garmhausen, Marius, Giuseppe Stirparo, Giuliano, Huth, Michelle, Titz‐Teixeira, Fabian, van der Lelij, Petra, Ramesmayer, Julia, Thomas, Henry F, Ralser, Meryem, Santini, Laura, Galimberti, Elena, Sarov, Mihail, Stewart, A Francis, Smith, Austin, Beyer, Andreas, Leeb, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047444/
https://www.ncbi.nlm.nih.gov/pubmed/33687089
http://dx.doi.org/10.15252/embj.2020105776

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