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Scrub eschar

A 60-year-old female presented to the emergency room with fever and myalgias for four days and shortness of breath for two days. On clinical examination, she was tachypneic and blood oxygen saturation of 86 % on room air. There was an eschar of size 1 × 1 cm on the left infraclavicular area (Fig. 1)...

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Autores principales: Pal Grewal, Tejinder, Kumar H, Mohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047456/
https://www.ncbi.nlm.nih.gov/pubmed/33889487
http://dx.doi.org/10.1016/j.idcr.2021.e01086
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author Pal Grewal, Tejinder
Kumar H, Mohan
author_facet Pal Grewal, Tejinder
Kumar H, Mohan
author_sort Pal Grewal, Tejinder
collection PubMed
description A 60-year-old female presented to the emergency room with fever and myalgias for four days and shortness of breath for two days. On clinical examination, she was tachypneic and blood oxygen saturation of 86 % on room air. There was an eschar of size 1 × 1 cm on the left infraclavicular area (Fig. 1). Chest examination showed bilateral interscapular crepitations. CXR showed bilateral lower zone infiltrates. Scrub typhus IgM was found to be positive by rapid diagnostic kit test, Eschar biopsy was also positive for scrub typhus by Polymerase Chain Reaction. The patient was started on doxycycline, clinically improved and discharged after ten days. Presence of eschars is considered pathognomonic of scrub typhus. Incidence of eschar varies widely from 7 % to 97 %. The main reason for low detection is eschars being missed on routine clinical examination as these are painless lesions consisting of a black scab, with an erythematous halo and minimal edema. Eschars are usually found over the covered areas of the body, such as the groin, axilla, chest, and lower back which appears a few days after at chigger-bite sites, even before the disease manifestation. This case emphasizes the importance of thorough clinical examination to look for eschar and early diagnosis and initiation of treatment while routine laboratory assays are awaited.
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spelling pubmed-80474562021-04-21 Scrub eschar Pal Grewal, Tejinder Kumar H, Mohan IDCases Case Illustrated A 60-year-old female presented to the emergency room with fever and myalgias for four days and shortness of breath for two days. On clinical examination, she was tachypneic and blood oxygen saturation of 86 % on room air. There was an eschar of size 1 × 1 cm on the left infraclavicular area (Fig. 1). Chest examination showed bilateral interscapular crepitations. CXR showed bilateral lower zone infiltrates. Scrub typhus IgM was found to be positive by rapid diagnostic kit test, Eschar biopsy was also positive for scrub typhus by Polymerase Chain Reaction. The patient was started on doxycycline, clinically improved and discharged after ten days. Presence of eschars is considered pathognomonic of scrub typhus. Incidence of eschar varies widely from 7 % to 97 %. The main reason for low detection is eschars being missed on routine clinical examination as these are painless lesions consisting of a black scab, with an erythematous halo and minimal edema. Eschars are usually found over the covered areas of the body, such as the groin, axilla, chest, and lower back which appears a few days after at chigger-bite sites, even before the disease manifestation. This case emphasizes the importance of thorough clinical examination to look for eschar and early diagnosis and initiation of treatment while routine laboratory assays are awaited. Elsevier 2021-03-26 /pmc/articles/PMC8047456/ /pubmed/33889487 http://dx.doi.org/10.1016/j.idcr.2021.e01086 Text en © 2021 Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Illustrated
Pal Grewal, Tejinder
Kumar H, Mohan
Scrub eschar
title Scrub eschar
title_full Scrub eschar
title_fullStr Scrub eschar
title_full_unstemmed Scrub eschar
title_short Scrub eschar
title_sort scrub eschar
topic Case Illustrated
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047456/
https://www.ncbi.nlm.nih.gov/pubmed/33889487
http://dx.doi.org/10.1016/j.idcr.2021.e01086
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