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Pharmacophore model, docking, QSAR, and molecular dynamics simulation studies of substituted cyclic imides and herbal medicines as COX-2 inhibitors

Cyclooxygenase-2 (COX-2) enzyme inhibitors have not eliminated the necessity for developed drugs not only in the nonsteroidal anti-inflammatory drug (NSAIDs) area, but also in other therapeutic applications including prevention of cancer and Alzheimer's disease. A series of novel substituted cy...

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Detalles Bibliográficos
Autores principales:	Moussa, Nathalie, Hassan, Ahmad, Gharaghani, Sajjad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047494/ https://www.ncbi.nlm.nih.gov/pubmed/33889764 http://dx.doi.org/10.1016/j.heliyon.2021.e06605

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