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Single-cell RNA-seq reveals dynamic change in tumor microenvironment during pancreatic ductal adenocarcinoma malignant progression

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is most aggressive among all gastrointestinal tumors. The complex intra-tumor heterogeneity and special tumor microenvironment in PDAC bring great challenges for developing effective treatment strategies. We aimed to delineate dynamic changes of tu...

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Detalles Bibliográficos
Autores principales:	Chen, Kai, Wang, Qi, Li, Mingzhe, Guo, Huahu, Liu, Weikang, Wang, Feng, Tian, Xiaodong, Yang, Yinmo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047497/ https://www.ncbi.nlm.nih.gov/pubmed/33819739 http://dx.doi.org/10.1016/j.ebiom.2021.103315

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