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The gut microbiome influences the bioavailability of olanzapine in rats

BACKGROUND: The role of the gut microbiome in the biotransformation of drugs has recently come under scrutiny. It remains unclear whether the gut microbiome directly influences the extent of drug absorbed after oral administration and thus potentially alters clinical pharmacokinetics. METHODS: In th...

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Detalles Bibliográficos
Autores principales:	Cussotto, Sofia, Walsh, Jacinta, Golubeva, Anna V., Zhdanov, Alexander V., Strain, Conall R., Fouhy, Fiona, Stanton, Catherine, Dinan, Timothy G., Hyland, Niall P., Clarke, Gerard, Cryan, John F., Griffin, Brendan T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047500/ https://www.ncbi.nlm.nih.gov/pubmed/33819741 http://dx.doi.org/10.1016/j.ebiom.2021.103307

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