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Intracellular interferon signalling pathways as potential regulators of covalently closed circular DNA in the treatment of chronic hepatitis B

Infection with the hepatitis B virus (HBV) is still a major global health threat as 250 million people worldwide continue to be chronically infected with the virus. While patients may be treated with nucleoside/nucleotide analogues, this only suppresses HBV titre to sub-detection levels without elim...

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Detalles Bibliográficos
Autores principales: Goh, Zhi Yi, Ren, Ee Chee, Ko, Hui Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047536/
https://www.ncbi.nlm.nih.gov/pubmed/33911462
http://dx.doi.org/10.3748/wjg.v27.i14.1369