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STING and cGAS gene expressions were downregulated among HIV-1-infected persons after antiretroviral therapy

BACKGROUND: The HIV-1 epidemic is still considered a global public health problem, but great advances have been made in fighting it by antiretroviral therapy (ART). ART has a considerable impact on viral replication and host immunity. The production of type I interferon (IFN) is key to the innate im...

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Detalles Bibliográficos
Autores principales: de Lima, Lorena Leticia Peixoto, de Oliveira, Allysson Quintino Tenório, Moura, Tuane Carolina Ferreira, da Silva Graça Amoras, Ednelza, Lima, Sandra Souza, da Silva, Andrea Nazaré Monteiro Rangel, Queiroz, Maria Alice Freitas, Cayres-Vallinoto, Izaura Maria Vieira, Ishak, Ricardo, Vallinoto, Antonio Carlos Rosário
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047565/
https://www.ncbi.nlm.nih.gov/pubmed/33858455
http://dx.doi.org/10.1186/s12985-021-01548-6