Practical Synthesis and Application of Halogen-Doped Pyrrole Building Blocks

[Image: see text] A practical access to four new halogen-substituted pyrrole building blocks was realized in two to five synthetic steps from commercially available starting materials. The target compounds were prepared on a 50 mg to 1 g scale, and their conversion to nanomolar inhibitors of bacteri...

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Detalles Bibliográficos
Autores principales: Cotman, Andrej Emanuel, Guérin, Thomas, Kovačević, Ivana, Benedetto Tiz, Davide, Durcik, Martina, Fulgheri, Federica, Možina, Štefan, Secci, Daniela, Sterle, Maša, Ilaš, Janez, Zega, Anamarija, Zidar, Nace, Mašič, Lucija Peterlin, Tomašič, Tihomir, Leroux, Frédéric R., Hanquet, Gilles, Kikelj, Danijel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047689/
https://www.ncbi.nlm.nih.gov/pubmed/33869952
http://dx.doi.org/10.1021/acsomega.1c00331

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