Long-Term Persistence of Serum-Specific Anti-Chikungunya IgM Antibody - A Case Series of Brazilian Patients

The persistence of serum-specific anti-chikungunya IgM antibodies (CHIKV-IgM) can vary after chikungunya fever (CHIK) infection. However, the factors related to its production are not yet known. We described a case series drawn up from data collected from 57 patients between 12 and 36 months after t...

Descripción completa

Detalles Bibliográficos
Autores principales: Costa, Denise Maria do Nascimento, Coêlho, Maria Rosângela Cunha Duarte, Gouveia, Pedro Alves da Cruz, Bezerra, Luan Araújo, Marques, Claudia Diniz Lopes, Duarte, Angela Luzia Branco Pinto, Valente, Lucila Maria, Magalhães, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047711/
https://www.ncbi.nlm.nih.gov/pubmed/33886823
http://dx.doi.org/10.1590/0037-8682-0855-2020
Descripción
Sumario:The persistence of serum-specific anti-chikungunya IgM antibodies (CHIKV-IgM) can vary after chikungunya fever (CHIK) infection. However, the factors related to its production are not yet known. We described a case series drawn up from data collected from 57 patients between 12 and 36 months after the acute phase of CHIK infection in Northeastern Brazil. CHIKV-IgM was detectable in 7/57 (12.3%) patients after 28.3 months of infection. No frequency differences in chronic musculoskeletal manifestations and underlying conditions were detected between patients with or without CHIKV-IgM. CHIKV-IgM was detected for up to 35 months in Brazilian patients after CHIK infection.

Ejemplares similares