Long-Term Persistence of Serum-Specific Anti-Chikungunya IgM Antibody - A Case Series of Brazilian Patients

The persistence of serum-specific anti-chikungunya IgM antibodies (CHIKV-IgM) can vary after chikungunya fever (CHIK) infection. However, the factors related to its production are not yet known. We described a case series drawn up from data collected from 57 patients between 12 and 36 months after t...

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Autores principales: Costa, Denise Maria do Nascimento, Coêlho, Maria Rosângela Cunha Duarte, Gouveia, Pedro Alves da Cruz, Bezerra, Luan Araújo, Marques, Claudia Diniz Lopes, Duarte, Angela Luzia Branco Pinto, Valente, Lucila Maria, Magalhães, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047711/
https://www.ncbi.nlm.nih.gov/pubmed/33886823
http://dx.doi.org/10.1590/0037-8682-0855-2020
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author Costa, Denise Maria do Nascimento
Coêlho, Maria Rosângela Cunha Duarte
Gouveia, Pedro Alves da Cruz
Bezerra, Luan Araújo
Marques, Claudia Diniz Lopes
Duarte, Angela Luzia Branco Pinto
Valente, Lucila Maria
Magalhães, Vera
author_facet Costa, Denise Maria do Nascimento
Coêlho, Maria Rosângela Cunha Duarte
Gouveia, Pedro Alves da Cruz
Bezerra, Luan Araújo
Marques, Claudia Diniz Lopes
Duarte, Angela Luzia Branco Pinto
Valente, Lucila Maria
Magalhães, Vera
author_sort Costa, Denise Maria do Nascimento
collection PubMed
description The persistence of serum-specific anti-chikungunya IgM antibodies (CHIKV-IgM) can vary after chikungunya fever (CHIK) infection. However, the factors related to its production are not yet known. We described a case series drawn up from data collected from 57 patients between 12 and 36 months after the acute phase of CHIK infection in Northeastern Brazil. CHIKV-IgM was detectable in 7/57 (12.3%) patients after 28.3 months of infection. No frequency differences in chronic musculoskeletal manifestations and underlying conditions were detected between patients with or without CHIKV-IgM. CHIKV-IgM was detected for up to 35 months in Brazilian patients after CHIK infection.
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spelling pubmed-80477112021-04-16 Long-Term Persistence of Serum-Specific Anti-Chikungunya IgM Antibody - A Case Series of Brazilian Patients Costa, Denise Maria do Nascimento Coêlho, Maria Rosângela Cunha Duarte Gouveia, Pedro Alves da Cruz Bezerra, Luan Araújo Marques, Claudia Diniz Lopes Duarte, Angela Luzia Branco Pinto Valente, Lucila Maria Magalhães, Vera Rev Soc Bras Med Trop Case Report The persistence of serum-specific anti-chikungunya IgM antibodies (CHIKV-IgM) can vary after chikungunya fever (CHIK) infection. However, the factors related to its production are not yet known. We described a case series drawn up from data collected from 57 patients between 12 and 36 months after the acute phase of CHIK infection in Northeastern Brazil. CHIKV-IgM was detectable in 7/57 (12.3%) patients after 28.3 months of infection. No frequency differences in chronic musculoskeletal manifestations and underlying conditions were detected between patients with or without CHIKV-IgM. CHIKV-IgM was detected for up to 35 months in Brazilian patients after CHIK infection. Sociedade Brasileira de Medicina Tropical - SBMT 2021-04-12 /pmc/articles/PMC8047711/ /pubmed/33886823 http://dx.doi.org/10.1590/0037-8682-0855-2020 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Case Report
Costa, Denise Maria do Nascimento
Coêlho, Maria Rosângela Cunha Duarte
Gouveia, Pedro Alves da Cruz
Bezerra, Luan Araújo
Marques, Claudia Diniz Lopes
Duarte, Angela Luzia Branco Pinto
Valente, Lucila Maria
Magalhães, Vera
Long-Term Persistence of Serum-Specific Anti-Chikungunya IgM Antibody - A Case Series of Brazilian Patients
title Long-Term Persistence of Serum-Specific Anti-Chikungunya IgM Antibody - A Case Series of Brazilian Patients
title_full Long-Term Persistence of Serum-Specific Anti-Chikungunya IgM Antibody - A Case Series of Brazilian Patients
title_fullStr Long-Term Persistence of Serum-Specific Anti-Chikungunya IgM Antibody - A Case Series of Brazilian Patients
title_full_unstemmed Long-Term Persistence of Serum-Specific Anti-Chikungunya IgM Antibody - A Case Series of Brazilian Patients
title_short Long-Term Persistence of Serum-Specific Anti-Chikungunya IgM Antibody - A Case Series of Brazilian Patients
title_sort long-term persistence of serum-specific anti-chikungunya igm antibody - a case series of brazilian patients
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047711/
https://www.ncbi.nlm.nih.gov/pubmed/33886823
http://dx.doi.org/10.1590/0037-8682-0855-2020
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