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From Pure Antagonists to Pure Degraders of the Estrogen Receptor: Evolving Strategies for the Same Target
[Image: see text] Pure antiestrogens, or selective estrogen receptor degraders (SERDs), have proven to be effective in treating breast cancer that has progressed on tamoxifen and/or aromatase inhibitors. However, the only FDA-approved pure antiestrogen, fulvestrant, is limited in efficacy by its low...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047716/ https://www.ncbi.nlm.nih.gov/pubmed/33869913 http://dx.doi.org/10.1021/acsomega.0c06362 |