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Upregulation of antioxidant and autophagy pathways via NRF2 activation protects spinal cord neurons from ozone damage

Ozone therapy can relieve multiple types of pain but exhibits potential neurotoxicity, the mechanism of which is unclear. The present study aimed to identify the role of nuclear factor (erythroid-derived-2)-related 2 (NRF2) in preventing spinal cord injury caused by ozone overdose. Primary neuronal...

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Detalles Bibliográficos
Autores principales: Zhang, Cong, Ma, Shulin, Zhao, Xu, Wen, Bei, Sun, Panpan, Fu, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047762/
https://www.ncbi.nlm.nih.gov/pubmed/33846774
http://dx.doi.org/10.3892/mmr.2021.12067