Structure, Dynamics, Receptor Binding, and Antibody Binding of the Fully Glycosylated Full-Length SARS-CoV-2 Spike Protein in a Viral Membrane

[Image: see text] The spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mediates host cell entry by binding to angiotensin-converting enzyme 2 (ACE2) and is considered the major target for drug and vaccine development. We previously built fully glycosylated full-lengt...

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Autores principales: Choi, Yeol Kyo, Cao, Yiwei, Frank, Martin, Woo, Hyeonuk, Park, Sang-Jun, Yeom, Min Sun, Croll, Tristan I., Seok, Chaok, Im, Wonpil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047829/
https://www.ncbi.nlm.nih.gov/pubmed/33689337
http://dx.doi.org/10.1021/acs.jctc.0c01144

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