Cargando…

Experimental infection with the hookworm, Necator americanus, is associated with stable gut microbial diversity in human volunteers with relapsing multiple sclerosis

BACKGROUND: Helminth-associated changes in gut microbiota composition have been hypothesised to contribute to the immune-suppressive properties of parasitic worms. Multiple sclerosis is an immune-mediated autoimmune disease of the central nervous system whose pathophysiology has been linked to imbal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jenkins, Timothy P., Pritchard, David I., Tanasescu, Radu, Telford, Gary, Papaiakovou, Marina, Scotti, Riccardo, Cortés, Alba, Constantinescu, Cris S., Cantacessi, Cinzia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048248/ https://www.ncbi.nlm.nih.gov/pubmed/33853585 http://dx.doi.org/10.1186/s12915-021-01003-6

Ejemplares similares

Genome of the human hookworm Necator americanus
por: Tang, Yat T., et al.
Publicado: (2014)

The physicochemical fingerprint of Necator americanus
por: Chauhan, Veeren M., et al.
Publicado: (2017)

Correction: The physicochemical fingerprint of Necator americanus
por: Chauhan, Veeren M., et al.
Publicado: (2022)

Comprehensive analysis of the secreted proteome of adult Necator americanus hookworms
por: Logan, Jayden, et al.
Publicado: (2020)

Massively Parallel Sequencing and Analysis of the Necator americanus Transcriptome
por: Cantacessi, Cinzia, et al.
Publicado: (2010)

Necator americanus and Helminth Co-Infections: Further Down-Modulation of Hookworm-Specific Type 1 Immune Responses
por: Geiger, Stefan Michael, et al.
Publicado: (2011)

An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection
por: Pearson, Mark S., et al.
Publicado: (2009)

An Absence of Epstein–Barr Virus Reactivation and Associations with Disease Activity in People with Multiple Sclerosis Undergoing Therapeutic Hookworm Vaccination
por: Maple, Peter A. C., et al.
Publicado: (2020)

Development and evaluation of a Loop Mediated Isothermal Amplification (LAMP) technique for the detection of hookworm (Necator americanus) infection in fecal samples
por: Mugambi, Robert Muriuki, et al.
Publicado: (2015)

Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine
por: Seid, Christopher A, et al.
Publicado: (2015)

X-ray structures of Na-GST-1 and Na-GST-2 two glutathione s-transferase from the human hookworm Necator americanus
por: Asojo, Oluwatoyin A, et al.
Publicado: (2007)

Optimization and revision of the production process of the Necator americanus glutathione S-transferase 1 (Na-GST-1), the lead hookworm vaccine recombinant protein candidate
por: Curti, Elena, et al.
Publicado: (2014)

Risk profiling and efficacy of albendazole against the hookworms Necator americanus and Ancylostoma ceylanicum in Cambodia to support control programs in Southeast Asia and the Western Pacific
por: Colella, Vito, et al.
Publicado: (2021)

Stage-specific immune responses in human Necator americanus infection
por: GEIGER, S M, et al.
Publicado: (2007)

A Case of Severe Anemia by Necator americanus Infection in Korea
por: Hyun, Hee Jae, et al.
Publicado: (2010)

The production of Necator americanus larvae for use in experimental human infection
por: Chapman, Paul R., et al.
Publicado: (2022)

Epidemiology of soil-transmitted helminths using quantitative PCR and risk factors for hookworm and Necator americanus infection in school children in Dak Lak province, Vietnam
por: Hughes, Angus, et al.
Publicado: (2023)

Vaccination of human participants with attenuated Necator americanus hookworm larvae and human challenge in Australia: a dose-finding study and randomised, placebo-controlled, phase 1 trial
por: Chapman, Paul R, et al.
Publicado: (2021)

Identification of genetic variations in Necator americanus through resequencing by whole genome amplification
por: Liu, Yumei, et al.
Publicado: (2019)

Crystallization and preliminary X-ray analysis of Na-ASP-1, a multi-domain pathogenesis-related-1 protein from the human hookworm parasite Necator americanus. Corrigendum
por: Asojo, Oluwatoyin A., et al.
Publicado: (2010)

Cytokine profiles of Necator americanus and Plasmodium falciparum co-infected patients in rural Ghana
por: Amoani, Benjamin, et al.
Publicado: (2019)

Dynamics of the bacterial gut microbiota during controlled human infection with Necator americanus larvae
por: Ducarmon, Q. R., et al.
Publicado: (2020)

Computer-aided identification of potential inhibitors against Necator americanus glutathione S-transferase 3
por: Kwofie, Samuel K., et al.
Publicado: (2022)

Molecular Detection of Ancylostoma duodenale, Ancylostoma ceylanicum, and Necator americanus in Humans in Northeastern and Southern Thailand
por: Phosuk, Issarapong, et al.
Publicado: (2013)

Morphological and Molecular Diagnosis of Necator americanus and Ancylostoma ceylanicum Recovered from Villagers in Northern Cambodia
por: Chang, Taehee, et al.
Publicado: (2020)

Isothermal Diagnostic Assays for Monitoring Single Nucleotide Polymorphisms in Necator americanus Associated with Benzimidazole Drug Resistance
por: Rashwan, Nour, et al.
Publicado: (2016)

Elevated Serum IgG4 Levels in a Young Patient with Polyserositis and Necator americanus Infection
por: Sanna, Giuseppe D., et al.
Publicado: (2018)

An environmental assessment and risk map of Ascaris lumbricoides and Necator americanus distributions in Manufahi District, Timor-Leste
por: Wardell, Rebecca, et al.
Publicado: (2017)

Adult hookworms (Necator spp.) collected from researchers working with wild western lowland gorillas
por: Kalousová, Barbora, et al.
Publicado: (2016)

Role of oral teriflunomide in the management of multiple sclerosis
por: Tanasescu, Radu, et al.
Publicado: (2013)

Necator americanus Infection: A Possible Cause of Altered Dendritic Cell Differentiation and Eosinophil Profile in Chronically Infected Individuals
por: Fujiwara, Ricardo T., et al.
Publicado: (2009)

Use of quantitative PCR to assess the efficacy of albendazole against Necator americanus and Ascaris spp. in Manufahi District, Timor-Leste
por: Vaz Nery, Susana, et al.
Publicado: (2018)

A Functional Comparison of Homopentameric Nicotinic Acetylcholine Receptors (ACR-16) Receptors From Necator americanus and Ancylostoma ceylanicum
por: Kaji, Mark D., et al.
Publicado: (2020)

Improving stool sample processing and pyrosequencing for quantifying benzimidazole resistance alleles in Trichuris trichiura and Necator americanus pooled eggs
por: Gandasegui, Javier, et al.
Publicado: (2021)

MICHELINdb: a web-based tool for mining of helminth-microbiota interaction datasets, and a meta-analysis of current research
por: Scotti, Riccardo, et al.
Publicado: (2020)

An update on the use of sphingosine 1-phosphate receptor modulators for the treatment of relapsing multiple sclerosis
por: Dumitrescu, Laura, et al.
Publicado: (2023)

PCR-RFLP screening of polymorphisms associated with benzimidazole resistance in Necator americanus and Ascaris lumbricoides from different geographical regions in Brazil
por: Zuccherato, Luciana Werneck, et al.
Publicado: (2018)

Granulocyte-Macrophage Colony-Stimulating Factor as a Therapeutic Target in Multiple Sclerosis
por: Aram, Jehan, et al.
Publicado: (2018)

CSF lymphocytic pleocytosis does not predict a less favourable long-term prognosis in MS
por: Astbury, Lauren, et al.
Publicado: (2022)

Molecular modelling and de novo fragment-based design of potential inhibitors of beta-tubulin gene of Necator americanus from natural products
por: Agyapong, Odame, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_gmhjcbe2qq4rj9pgdlg6tfo28r