Cargando…
TNFα secreted by glioma associated macrophages promotes endothelial activation and resistance against anti-angiogenic therapy
One of the most prominent features of glioblastoma (GBM) is hyper-vascularization. Bone marrow-derived macrophages are actively recruited to the tumor and referred to as glioma-associated macrophages (GAMs) which are thought to provide a critical role in tumor neo-vascularization. However, the mecha...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048292/ https://www.ncbi.nlm.nih.gov/pubmed/33853689 http://dx.doi.org/10.1186/s40478-021-01163-0 |