Human alpha-synuclein overexpressing MBP29 mice mimic functional and structural hallmarks of the cerebellar subtype of multiple system atrophy

Multiple system atrophy (MSA) is a rare, but fatal atypical parkinsonian disorder. The prototypical pathological hallmark are oligodendroglial cytoplasmic inclusions (GCIs) containing alpha-synuclein (α-syn). Currently, two MSA phenotypes are classified: the parkinsonian (MSA-P) and the cerebellar s...

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Detalles Bibliográficos
Autores principales: Mészáros, Lisa, Riemenschneider, Markus J., Gassner, Heiko, Marxreiter, Franz, von Hörsten, Stephan, Hoffmann, Alana, Winkler, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048356/
https://www.ncbi.nlm.nih.gov/pubmed/33853667
http://dx.doi.org/10.1186/s40478-021-01166-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048356/
https://www.ncbi.nlm.nih.gov/pubmed/33853667
http://dx.doi.org/10.1186/s40478-021-01166-x

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