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Human alpha-synuclein overexpressing MBP29 mice mimic functional and structural hallmarks of the cerebellar subtype of multiple system atrophy

Multiple system atrophy (MSA) is a rare, but fatal atypical parkinsonian disorder. The prototypical pathological hallmark are oligodendroglial cytoplasmic inclusions (GCIs) containing alpha-synuclein (α-syn). Currently, two MSA phenotypes are classified: the parkinsonian (MSA-P) and the cerebellar s...

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Detalles Bibliográficos
Autores principales:	Mészáros, Lisa, Riemenschneider, Markus J., Gassner, Heiko, Marxreiter, Franz, von Hörsten, Stephan, Hoffmann, Alana, Winkler, Jürgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048356/ https://www.ncbi.nlm.nih.gov/pubmed/33853667 http://dx.doi.org/10.1186/s40478-021-01166-x

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