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Unknown uncertainties in the COVID-19 pandemic: Multi-dimensional identification and mathematical modelling for the analysis and estimation of the casualties

Insights about the dominant dynamics, coupled structures and the unknown uncertainties of the pandemic diseases play an important role in determining the future characteristics of the pandemic diseases. To enhance the prediction capabilities of the models, properties of the unknown uncertainties in...

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Autores principales: Tutsoy, Onder, Balikci, Kemal, Ozdil, Naime Filiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048408/
https://www.ncbi.nlm.nih.gov/pubmed/33879984
http://dx.doi.org/10.1016/j.dsp.2021.103058
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author Tutsoy, Onder
Balikci, Kemal
Ozdil, Naime Filiz
author_facet Tutsoy, Onder
Balikci, Kemal
Ozdil, Naime Filiz
author_sort Tutsoy, Onder
collection PubMed
description Insights about the dominant dynamics, coupled structures and the unknown uncertainties of the pandemic diseases play an important role in determining the future characteristics of the pandemic diseases. To enhance the prediction capabilities of the models, properties of the unknown uncertainties in the pandemic disease, which can be utterly random, or function of the system dynamics, or it can be correlated with an unknown function, should be determined. The known structures and amount of the uncertainties can also help the state authorities to improve the policies based on the recognized source of the uncertainties. For instance, the uncertainties correlated with an unknown function imply existence of an undetected factor in the casualties. In this paper, we extend the SpID-N (Suspicious-Infected-Death with non-pharmacological policies) model as in the form of MIMO (Multi-Input-Multi-Output) structure by adding the multi-dimensional unknown uncertainties. The results confirm that the infected and death sub-models mostly have random uncertainties (due undetected casualties) whereas the suspicious sub-model has uncertainties correlated with the internal dynamics (governmental policy of increasing the number of the daily tests) for Turkey. However, since the developed MIMO model parameters are learned from the data (daily reported casualties), it can be easily adapted for other countries. Obtained model with the corresponding uncertainties predicts a distinctive second peak where the number of deaths, infected and suspicious casualties disappear in 240, 290, and more than 300 days, respectively, for Turkey.
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spelling pubmed-80484082021-04-16 Unknown uncertainties in the COVID-19 pandemic: Multi-dimensional identification and mathematical modelling for the analysis and estimation of the casualties Tutsoy, Onder Balikci, Kemal Ozdil, Naime Filiz Digit Signal Process Article Insights about the dominant dynamics, coupled structures and the unknown uncertainties of the pandemic diseases play an important role in determining the future characteristics of the pandemic diseases. To enhance the prediction capabilities of the models, properties of the unknown uncertainties in the pandemic disease, which can be utterly random, or function of the system dynamics, or it can be correlated with an unknown function, should be determined. The known structures and amount of the uncertainties can also help the state authorities to improve the policies based on the recognized source of the uncertainties. For instance, the uncertainties correlated with an unknown function imply existence of an undetected factor in the casualties. In this paper, we extend the SpID-N (Suspicious-Infected-Death with non-pharmacological policies) model as in the form of MIMO (Multi-Input-Multi-Output) structure by adding the multi-dimensional unknown uncertainties. The results confirm that the infected and death sub-models mostly have random uncertainties (due undetected casualties) whereas the suspicious sub-model has uncertainties correlated with the internal dynamics (governmental policy of increasing the number of the daily tests) for Turkey. However, since the developed MIMO model parameters are learned from the data (daily reported casualties), it can be easily adapted for other countries. Obtained model with the corresponding uncertainties predicts a distinctive second peak where the number of deaths, infected and suspicious casualties disappear in 240, 290, and more than 300 days, respectively, for Turkey. Elsevier Inc. 2021-07 2021-04-15 /pmc/articles/PMC8048408/ /pubmed/33879984 http://dx.doi.org/10.1016/j.dsp.2021.103058 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Tutsoy, Onder
Balikci, Kemal
Ozdil, Naime Filiz
Unknown uncertainties in the COVID-19 pandemic: Multi-dimensional identification and mathematical modelling for the analysis and estimation of the casualties
title Unknown uncertainties in the COVID-19 pandemic: Multi-dimensional identification and mathematical modelling for the analysis and estimation of the casualties
title_full Unknown uncertainties in the COVID-19 pandemic: Multi-dimensional identification and mathematical modelling for the analysis and estimation of the casualties
title_fullStr Unknown uncertainties in the COVID-19 pandemic: Multi-dimensional identification and mathematical modelling for the analysis and estimation of the casualties
title_full_unstemmed Unknown uncertainties in the COVID-19 pandemic: Multi-dimensional identification and mathematical modelling for the analysis and estimation of the casualties
title_short Unknown uncertainties in the COVID-19 pandemic: Multi-dimensional identification and mathematical modelling for the analysis and estimation of the casualties
title_sort unknown uncertainties in the covid-19 pandemic: multi-dimensional identification and mathematical modelling for the analysis and estimation of the casualties
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048408/
https://www.ncbi.nlm.nih.gov/pubmed/33879984
http://dx.doi.org/10.1016/j.dsp.2021.103058
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