Cargando…

An Integrative Pharmacology-Based Strategy to Uncover the Mechanism of Xiong-Pi-Fang in Treating Coronary Heart Disease with Depression

Objectives: This study aimed to explore the mechanism of Xiong-Pi-Fang (XPF) in the treatment of coronary heart disease (CHD) with depression by an integrative strategy combining serum pharmacochemistry, network pharmacology analysis, and experimental validation. Methods: An ultrahigh performance li...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Lihong, Zhang, Yu, Zhu, Mingdan, Pei, Limin, Deng, Fangjun, Chen, JinHong, Zhang, Shaoqiang, Cong, Zidong, Du, Wuxun, Xiao, Xuefeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048422/ https://www.ncbi.nlm.nih.gov/pubmed/33867976 http://dx.doi.org/10.3389/fphar.2021.590602

Ejemplares similares

Integrating Pharmacokinetics Study, Network Analysis, and Experimental Validation to Uncover the Mechanism of Qiliqiangxin Capsule Against Chronic Heart Failure
por: Zhang, Yu, et al.
Publicado: (2019)

Wenxin Keli for the Treatment of Arrhythmia—Systems Pharmacology and In Vivo Pharmacological Assessment
por: Li, Xiaofeng, et al.
Publicado: (2021)

Network Pharmacology and Metabolomics Studies on Antimigraine Mechanisms of Da Chuan Xiong Fang (DCXF)
por: Ma, Shiyu, et al.
Publicado: (2021)

Metabolomics Study of the Biochemical Changes in the Plasma of Myocardial Infarction Patients
por: Zhu, Mingdan, et al.
Publicado: (2018)

An Integrative Pharmacology-Based Pattern to Uncover the Pharmacological Mechanism of Ginsenoside H Dripping Pills in the Treatment of Depression
por: Zhao, Libin, et al.
Publicado: (2021)

Reply to Liu and Xiong
por: He, Heng, et al.
Publicado: (2022)

Integrated Network Pharmacology and Metabolomics Analysis of the Therapeutic Effects of Zi Dian Fang on Immune Thrombocytopenic Purpura
por: Li, Yubo, et al.
Publicado: (2018)

Network pharmacology and in vivo experiment-based strategy to investigate mechanisms of JingFangFuZiLiZhong formula for ulcerative colitis
por: Wang, Mengyuan, et al.
Publicado: (2022)

Molecular mechanism of Ganji Fang in the treatment of hepatocellular carcinoma based on network pharmacology, molecular docking and experimental verification technology
por: Yang, Miaolun, et al.
Publicado: (2023)

Uncovering the Pharmacological Mechanisms of Gexia-Zhuyu Formula (GXZY) in Treating Liver Cirrhosis by an Integrative Pharmacology Strategy
por: Cao, Xu, et al.
Publicado: (2022)

Uncovering Bupi Yishen Formula Pharmacological Mechanisms Against Chronic Kidney Disease by Network Pharmacology and Experimental Validation
por: Zhang, Difei, et al.
Publicado: (2021)

Effect of GuiXiong Xiaoyi Wan in Treatment of Endometriosis on Rats
por: Jin, Zhixing, et al.
Publicado: (2015)

Winter Water Quality Modeling in Xiong’an New Area Supported by Hyperspectral Observation
por: Yang, Yuechao, et al.
Publicado: (2023)

Identify the Key Active Ingredients and Pharmacological Mechanisms of Compound XiongShao Capsule in Treating Diabetic Peripheral Neuropathy by Network Pharmacology Approach
por: Yu, Meixiang, et al.
Publicado: (2019)

Xiao-Yin-Fang Therapy Alleviates Psoriasis-like Skin Inflammation Through Suppressing γδT17 Cell Polarization
por: Zhang, Xilin, et al.
Publicado: (2021)

Zi Shen Wan Fang Attenuates Neuroinflammation and Cognitive Function Via Remodeling the Gut Microbiota in Diabetes-Induced Cognitive Impairment Mice
por: Shi, Jiangwei, et al.
Publicado: (2022)

Proteomic Analysis Provides Insights Into the Therapeutic Effect of GU-BEN-FANG-XIAO Decoction on a Persistent Asthmatic Mouse Model
por: Liu, Li-wei, et al.
Publicado: (2019)

Grey Relational Analysis Combined With Network Pharmacology to Identify Antioxidant Components and Uncover Its Mechanism From Moutan Cortex
por: Zhang, Yingchun, et al.
Publicado: (2021)

Targeting Neuroinflammation in Brain Cancer: Uncovering Mechanisms, Pharmacological Targets, and Neuropharmaceutical Developments
por: Alghamri, Mahmoud S., et al.
Publicado: (2021)

Siteng Fang Reverses Multidrug Resistance in Gastric Cancer: A Network Pharmacology and Molecular Docking Study
por: Guo, Lingjian, et al.
Publicado: (2021)

Effects of Chang-Kang-Fang Formula on the Microbiota-Gut-Brain Axis in Rats With Irritable Bowel Syndrome
por: Ling, Xiwen, et al.
Publicado: (2022)

The Chinese herbal medicine Dai-Zong-Fang promotes browning of white adipocytes in vivo and in vitro by activating PKA pathway to ameliorate obesity
por: Xu, Jing, et al.
Publicado: (2023)

Uncovering the pharmacology of Ginkgo biloba folium in the cell-type-specific targets of Parkinson’s disease
por: Yan, Yu-Chen, et al.
Publicado: (2022)

Uncovering the mechanism of Kang-ai injection for treating intrahepatic cholangiocarcinoma based on network pharmacology, molecular docking, and in vitro validation
por: Song, Fei, et al.
Publicado: (2023)

Uncovering the Mechanisms of Chinese Herbal Medicine (MaZiRenWan) for Functional Constipation by Focused Network Pharmacology Approach
por: Huang, Tao, et al.
Publicado: (2018)

Study on the causes of growth differences in three conifers after the rainy season in the Xiong’an New Area
por: Ran, Xin, et al.
Publicado: (2023)

Gu-Ben-Fang-Xiao Decoction Ameliorated Murine Asthma in Remission Stage by Modulating Microbiota-Acetate-Tregs Axis
por: Dong, Yingmei, et al.
Publicado: (2020)

Editorial: Targeting Neuroinflammation in Central Nervous System Disorders: Uncovering Mechanisms, Pharmacological Targets, and Neuropharmaceutical Developments
por: Pérez, Mariela Fernanda, et al.
Publicado: (2021)

White Fang /
por: London, Jack, 1876-1916
Publicado: (1998)

Fang Filling
Publicado: (1860)

Fang Filling
por: Shadoan, W. H.
Publicado: (1863)

Treatment of Fangs
por: Foote, Geo. F.
Publicado: (1863)

Fang Filling
por: Shadoan, W. H.
Publicado: (1859)

Fang Filling
por: Berry, A.
Publicado: (1859)

Fangs of the Rattlesnake
Publicado: (1883)

Tong-Xie-Yao-Fang Regulates 5-HT Level in Diarrhea Predominant Irritable Bowel Syndrome Through Gut Microbiota Modulation
por: Li, Junchen, et al.
Publicado: (2018)

Uncovering the Complexity Mechanism of Different Formulas Treatment for Rheumatoid Arthritis Based on a Novel Network Pharmacology Model
por: Wang, Ke-xin, et al.
Publicado: (2020)

Uncovering the Effect and Mechanism of Rhizoma Corydalis on Myocardial Infarction Through an Integrated Network Pharmacology Approach and Experimental Verification
por: Li, Jingyan, et al.
Publicado: (2022)

Landscape Pattern Evolution Processes of Wetlands and Their Driving Factors in the Xiong’an New Area of China
por: Yang, Miao, et al.
Publicado: (2021)

Uncovering the Pharmacological Mechanism of 2-Dodecyl-6-Methoxycyclohexa-2,5 -Diene-1,4-Dione Against Lung Cancer Based on Network Pharmacology and Experimental Evaluation
por: Wang, Lihui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7oei7t2ink2r494sa6erbi77cc