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Cryo‐EM Resolves Molecular Recognition Of An Optojasp Photoswitch Bound To Actin Filaments In Both Switch States

Actin is essential for key processes in all eukaryotic cells. Cellpermeable optojasps provide spatiotemporal control of the actin cytoskeleton, confining toxicity and potentially rendering F‐actin druggable by photopharmacology. Here, we report cryo electron microscopy (cryo‐EM) structures of both i...

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Detalles Bibliográficos
Autores principales:	Pospich, Sabrina, Küllmer, Florian, Nasufović, Veselin, Funk, Johanna, Belyy, Alexander, Bieling, Peter, Arndt, Hans‐Dieter, Raunser, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048601/ https://www.ncbi.nlm.nih.gov/pubmed/33449370 http://dx.doi.org/10.1002/anie.202013193

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