A Fibrosis‐Independent Hepatic Transcriptomic Signature Identifies Drivers of Disease Progression in Primary Sclerosing Cholangitis

BACKGROUND AND AIMS: Primary sclerosing cholangitis (PSC) is a heterogeneous cholangiopathy characterized by progressive biliary fibrosis. RNA sequencing of liver tissue from patients with PSC (n = 74) enrolled in a 96‐week clinical trial was performed to identify associations between biological pat...

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Detalles Bibliográficos
Autores principales: Gindin, Yevgeniy, Chung, Chuhan, Jiang, Zhaoshi, Zhou, Jing Zhu, Xu, Jun, Billin, Andrew N., Myers, Robert P., Goodman, Zachary, Landi, Abdolamir, Houghton, Michael, Green, Richard M., Levy, Cynthia, Kowdley, Kris V., Bowlus, Christopher L., Muir, Andrew J., Trauner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048608/
https://www.ncbi.nlm.nih.gov/pubmed/32745270
http://dx.doi.org/10.1002/hep.31488

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